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目的探讨多层螺旋CTA肠系膜上动脉显示中,应用低剂量低浓度对比剂注射方式的可行性。方法选取行肠系膜上动脉CTA检查的患者120例,分为常规组和双低组,每组患者各60例。常规组注射对比剂碘普罗胺(370mgI/ml),注射剂量根据体重计算(1.0ml/kg);双低组注射对比剂碘佛醇(320mgI/ml),注射剂量根据(体重×1.0ml/kg-10ml)计算。分别测量二组图像中肠系膜上动脉起始部和L_2椎体水平处的CT值。计算二组患者对比剂注射剂量。记录二组图像质量评分情况。结果常规组肠系膜上动脉起始部和L_2椎体水平处CT值与双低组肠系膜上动脉起始部和L_2椎体水平处CT值比较;差异有统计学意义(P<0.05)。常规组和双低组的对比剂用量分别为(68.07±9.59)ml和(57.09±9.41)ml,差异有统计学意义(P<0.05)。常规组和双低组的图像质量评分差异无统计学意义(P>0.05)。结论多层螺旋CT肠系膜上动脉CTA中,应用低剂量低浓度对比剂注射方式是可行的,可获得满足临床诊断要求的图像,且有效减少碘剂总量,降低肾毒性。
Objective To investigate the feasibility of low-dose and low-contrast contrast media injection in multi-slice spiral CTA superior mesenteric artery. Methods A total of 120 patients undergoing CTA of the superior mesenteric artery were enrolled in the study. They were divided into routine and double-low groups, 60 in each group. The control group was given iopromide (370mgI / ml) as control. The injection dose was based on body weight (1.0ml / kg); the control group received ioversol (320mgI / ml) kg-10ml). The CT values at the beginning of the superior mesenteric artery and the level of the L 2 vertebral body were measured in the two groups of images respectively. The two groups of patients were calculated contrast agent injection dose. Record two sets of image quality score. Results The CT value at the beginning of the superior mesenteric artery and the level of the L 2 vertebral body in the conventional group were significantly lower than those in the inferior group (P <0.05). The contrast agent dosage of conventional group and double low group were (68.07 ± 9.59) ml and (57.09 ± 9.41) ml respectively, the difference was statistically significant (P <0.05). There was no significant difference in the image quality scores between the conventional group and the double low group (P> 0.05). Conclusions Multi-slice spiral CT superior mesenteric artery CTA, low-dose low-contrast contrast agent injection is feasible, can meet the clinical diagnostic requirements of the image, and effectively reduce the total amount of iodine and reduce renal toxicity.