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目的回顾性比较腹腔镜前列腺癌根治性切除术(laparoscopic radical prostatectomy,LRP)对既往有无经尿道前列腺电切术(Transurethral Resection of the prostate,TURP)者手术学、肿瘤学及功能学疗效的影响。方法 2012年3月至2015年9月间,116例前列腺癌患者于我院行了LRP术,其中12(10.3%)例患者既往曾行TURP术。回顾性比较其围手术期及术后相关指标。结果TURP组患者术后带管时间较长(P=0.003),pT3a期肿瘤比例较高(P=0.01),术后1-2年后性功能维持率较高(P<0.001)。虽然有TURP史患者术后3月时控尿率较低(P<0.001),但在其后的随访中该差异无统计学意义。结论既往TURP史不会显著影响LRP的手术难度及中期疗效。
Objective To retrospectively compare the effects of laparoscopic radical prostatectomy (LRP) on the surgical, oncologic and functional outcomes of patients with previous TURP (Transurethral Resection of the prostate, TURP) . Methods Between March 2012 and September 2015, 116 patients with prostate cancer underwent LRP surgery in our hospital. Among them, 12 (10.3%) had previous TURP. Retrospective comparison of its perioperative and postoperative related indicators. Results The duration of laparotomy in TURP group was longer (P = 0.003), the proportion of tumor in stage of pT3a was higher (P = 0.01), and the maintenance of sexual function was higher in 1-2 month after operation (P <0.001). Although patients with a history of TURP had a lower rate of control urine at 3 months after surgery (P <0.001), there was no significant difference in subsequent follow-up. Conclusion The previous history of TURP did not significantly affect the surgical difficulty and mid-term efficacy of LRP.