报告3例原发性支气管淀粉样变，分别以长期咳嗽咳痰、刺激性呛咳、咳嗽伴夜间喘憋为其临床表现，均经纤支镜活体组织嗜伊红染色，见均质嗜伊红物沉积于支气管粘膜下，病理诊断淀粉样变。经秋水仙碱、抗菌药及气管赘生物刮除术等治疗病情均明显好转。对其生化与免疫学变化、病理特点及治疗等进行了探讨。 The report of 3 cases of primary bronchial amyloidosis, respectively, with long-term cough and sputum, irritable cough, cough with wheeze at night were their clinical manifestations were fiberoptic bronchial tissue eosin staining, see homogeneous eosinophilia Red deposition in the bronchial mucosa, pathological diagnosis of amyloidosis. Colchicine, anti-bacterial drugs and tracheostomy curettage and other treatment conditions were significantly improved. Its biochemical and immunological changes, pathological features and treatment were discussed.