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背景 虽然供血机构可以知道保存前(PS)少白细胞(LR)成分和床边(BS)白细胞滤器的数量及分布情况,但是却不知道LR占总的血细胞成分输注的比例。因此,难以列出潜在的由BS转变为PS LR的清单。方法 1999年12月,对191所采血机构的与血小板输注(PTx)相关的负责人员和主管技师进行了调查。在美国范围内根据地理位置(22％北大西洋地区;27％东南部地区:16％北部中心地区;16％南部地区及18％西部地区)、主要供血机构(48％非红十字,52％红十字)和医院规模大小(43％>522床位;26％有300～500床位;31％<300床位,随机挑选调查对象。每月这些医院平均有184次PTx(范围为12～462),其中95％的为成人(范围为91％～99％)。结果 单采(AP)和混合全血制备的血小板(P—WBP)各占一半PTx。绝大多数接受PTx的是非骨髓移植的血液学-肿瘤学患者(52％),继之是心胸手术(CTS)患者和接受一般治疗(Gen Med)的患者(各占13％)。50％(外伤)到94％(骨髓移植(BMT))的PTx为LR,总计74％的PTx为TR。通常PS和BS这两种方法被采用的机会相当。
BACKGROUND Although blood donors can know the number and distribution of pre-conservation (PS) leukocyte (LR) components and bedside (BS) leukocyte filters, it is not known whether LR accounts for the proportion of total blood cell component infusions. Therefore, it is difficult to list a list of potential BS-to-PS LR conversions. Methods In December 1999, PTx-related staff responsible for platelet transfusion (PTx) and competent technicians were investigated in 191 blood collection facilities. In the U.S. based on geographic location (22% in the North Atlantic; 27% in the southeast: 16% in the north; 16% in the south, and 18% in the west), major blood donors (48% non-Red Cross, 52% red (Cross) and the size of the hospital (43%> 522 beds; 26% have 300-500 beds; 31% <300 beds, randomly selected subjects. Each month these hospitals have an average of 184 PTx (range, 12-462), among which 95% were adults (range 91% to 99%).Results Platelets (P-WBP) prepared from apheresis (AP) and mixed whole blood accounted for half of each PTx. The vast majority of patients who received PTx were hematopoietic from non-bone marrow transplantation. - Oncological patients (52%), followed by cardiothoracic surgery (CTS) patients and patients receiving Genmund (13% each), 50% (trauma) to 94% (bone marrow transplantation (BMT)) The PTx is LR, and a total of 74% of the PTx is TR. Normally the two methods PS and BS have the same chance of being used.