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目的探讨基底节钙化的发病因素、临床特点。方法总结分析23例头颅CT证实的基底节钙化的临床资料。结果以基底节钙化为主的脑内广泛对称性钙化中,原发性甲状旁腺功能减退(HPT)9例,Fahr病6例。其余分别是手术后甲状旁腺功能减退、脑囊虫、结节性硬化、CO中毒后、脑炎后、生理性钙化8例。结论基底节钙化最常见的病因为HPT及Fahr病,诊断需结合临床特点综合分析,明确病因,以防误诊、漏诊,经治疗大多患者症状能得以改善和控制。
Objective To investigate the pathogenesis and clinical features of basal ganglia calcification. Methods The clinical data of 23 cases with basal ganglia calcification confirmed by head CT were analyzed. Results Basal ganglia calcification in the brain extensive symmetrical calcification, 9 cases of primary hypoparathyroidism (HPT), Fahr disease in 6 cases. The remaining were postoperative parathyroid dysfunction, cerebral cysticercosis, tuberous sclerosis, CO poisoning, after encephalitis, physiological calcification in 8 cases. Conclusion The most common causality of basal ganglia calcification is HPT and Fahr disease. The diagnosis should be based on a comprehensive analysis of clinical features to clarify the cause to prevent misdiagnosis and missed diagnosis. The symptoms of most patients after treatment can be improved and controlled.