近年来大量研究表明microRNAs(miRNAs)与人类多种肿瘤的发生发展及侵袭转移存在着密切关系,miRNAs可能成为一类新的致癌基因或抑癌基因,它们通过抑制靶mRNA翻译或诱导靶mRNA降解在转录后水平调控基因表达,具有癌基因或抑癌基因的功能,参与肿瘤的发生、发展及侵袭转移。 In recent years, a large number of studies have shown that microRNAs (miRNAs) are closely related to the development, invasion and metastasis of many human tumors. MiRNAs may become a new type of oncogenes or tumor suppressor genes, which can inhibit target mRNA translation or induce target mRNA degradation Regulate gene expression at post-transcriptional level, have the function of oncogene or tumor suppressor gene, and participate in the occurrence, development, invasion and metastasis of tumors.