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AIM: To Observe the effect of change in oxygen tensionon the release pattern and nature of endothelium-derivedsubstances in isolated rabbit aorta. METHODS: Iso-metric contractions and relaxations in isolated rabbit stripwere observed in response to changes in oxygen tensionand effect of various drugs was noted on them. RE-SULTS: Change in oxygen tension from high [po_2=(618.9±0.4) mmHg; 1 mmHg= 133.3 Pa] to low[Po_2= (117.6± 0.6) mmHg] was observed to convert
AIM: To Observe the effect of change in oxygen tension on the release pattern and nature of endothelium-derivedsubstances in isolated rabbit aorta. METHODS: Iso-metric contractions and relaxations in isolated rabbit strip were observed in response to changes in oxygen tension and effect of various drugs was noted on them. RE-SULTS: Change in oxygen tension from high [po_2 = (618.9 ± 0.4) mmHg; 1 mmHg = 133.3 Pa] to low [Po_2 = (117.6 ± 0.6) mmHg] was observed to convert