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目的研究南京地区0~3岁婴幼儿的跟骨超声骨密度一般现状,为骨骼营养评价和疾病诊断提供依据。方法通过定量超声法测定南京地区20 479名0~3岁婴幼儿跟骨骨密度(Bone Mineral Density,BMD)。结果 0~3岁婴幼儿骨密度随着年龄的增长逐渐降低,18月龄后下降明显。各月龄女童BMD低于男童,差异有统计学意义(P<0.05)。随着月龄的增加,女童的Z-score值下降明显,尤其是在24月龄左右出现最低值。结论婴幼儿BMD受年龄和性别的影响,应重视>18月龄婴幼儿,尤其是女童的维生素D3和钙的补充。
Objective To study the general status of calcaneal bone mineral density (BMD) in infants and young children aged 0 ~ 3 years in Nanjing, and to provide evidence for the evaluation of bone nutrition and disease diagnosis. Methods Bone mineral density (BMD) was measured in 20 479 infants aged 0 ~ 3 years old in Nanjing by quantitative ultrasound method. Results The bone mineral density of infants aged 0 ~ 3 years decreased gradually with age and decreased significantly after 18 months. The BMD of girls of all ages was lower than that of boys, the difference was statistically significant (P <0.05). With the increase of age, the Z-score of girls decreased significantly, especially at the age of 24 months. Conclusion BMD in infants and young children affected by age and gender, should be emphasized> 18-year-old infants, especially girls vitamin D3 and calcium supplement.