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目的探讨急性心肌梗塞(AMI)患者球结膜微血栓的出现与QT间期离散度(QTd)、JT间期离散度(JTd)的关系。方法对AMI早期患者进行球结膜微循环检查 ,根据球结膜微循环中有无微血栓分为有血栓组与无血栓组 ,同时测量常规体表心电图QTd、JTd ,对AMI符合静脉溶栓条件者给予溶栓抗凝治疗。结果AMI患者QTd、JTd明显高于对照组(P<0.01),血栓组明显高于无栓组(P=0.01)微血栓出现的数量与QTd、JTd呈明显正相关(r=0.46P<0.01)。溶栓治疗后微血栓减少或消失后QTd、JTd渐减小。结论微血栓可能是QTd、JTd增加的原因之一 ,改善微循环、消除微血栓能够减少心室肌复极离散度。
Objective To investigate the relationship between QTd and JTd in patients with acute myocardial infarction (AMI). Methods According to the presence or absence of microthrombi in the conjunctival microcirculation, the conjunctival microcirculation examination was performed in patients with AMI in the early stage. The patients were divided into thrombosis group and thrombus-free group according to the presence or absence of microthrombosis. Meanwhile, routine surface electrocardiogram QTd and JTd were measured. Give thrombolytic anticoagulation. Results The QTd and JTd in patients with AMI were significantly higher than those in the control group (P <0.01). The number of microthrombi in the thrombosis group was significantly higher than that in the non-thrombosis group (P = 0.01) and the QTd and JTd were positively correlated (r = 0.46P <0.01 ). Thrombolytic therapy after the reduction or disappearance of micro-thrombosis QTd, JTd decreased gradually. Conclusion Micro-thrombus may be one of the reasons for the increase of QTd and JTd, and the improvement of microcirculation and elimination of micro-thrombus can reduce the ventricular repolarization dispersion.