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我院近年来对心衰病人在常规使用强心剂、利尿剂,抗感染、血管扩张剂等治疗1周后而心衰仍无明显改善,水肿明显,尿量较少的病人加用巯甲丙脯酸(CPT)口服,用药后心功能明显改善,无特殊不良反应,现报告如下。 1 临床资料 1.1 治疗对象 12例均为住院病人,男3例,女9例,年龄34～76岁。其中肺心病4例,高心病2例,风心病3例,心肌病2例,冠心病1例。临床症状均有胸闷、心慌、纳差、尿少。除心脏体征外,肝肿大9例,肝颈征7例,下肢浮肿8例,肺底湿罗音5例,心电图示心肌缺血4例。按NYHA心功能分级Ⅱ级者2例,Ⅲ级者6例,Ⅳ级者4例。 1.2 治疗方法 入院后均采用控制诱因、休息、限盐、强心、利尿、抗感染、血管扩张剂等综合治疗1周
In recent years, our hospital for heart failure patients in the conventional use of cardiac, diuretics, anti-infective, vasodilators and other treatment after 1 week and no significant improvement in heart failure, edema, less urine output with the addition of mercaptor Acid (CPT) oral, cardiac function improved significantly after treatment, no special adverse reactions, are as follows. 1 Clinical data 1.1 Treatment of 12 cases were hospitalized patients, 3 males and 9 females, aged 34 to 76 years. Of which 4 cases of pulmonary heart disease, heart disease in 2 cases, 3 cases of rheumatic heart disease, 2 cases of cardiomyopathy, coronary heart disease in 1 case. Clinical symptoms are chest tightness, palpitation, anorexia, oliguria. In addition to heart signs, hepatomegaly in 9 cases, hepatic neck in 7 cases, lower extremity edema in 8 cases, pulmonary rales in 5 cases, ECG showed myocardial ischemia in 4 cases. According to NYHA cardiac function grade 2 grade in 2 cases, grade 3 in 6 cases, grade 4 in 4 cases. 1.2 Treatment After admission are used to control incentives, rest, salt, cardiac, diuretic, anti-infective, vasodilator and other comprehensive treatment of 1 week