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扁桃体切除术普遍用局麻，少数病人在注射局麻药时突然发生意识丧失、惊厥、紫绀、呼吸停止、血压下降、甚至心跳停止而死亡等严重并发症。我们认为是中毒反应。在家兔身上所作毒力试验显示，同等剂量１％利多卡因在咽部粘膜与静脉注射各时间点血药浓度比较，血药浓度采用荧光偏振免疫法（ＦＰＬＡ）方法测定，在统计学上无明显差异（Ｐ＞００５）。说明麻药在血管丰富粘膜可被迅速吸收或可能麻药误入血管，瞬间麻药进入血液循环，超过机体的消除速率，麻药立即以很高血药浓度到达心脏和脑组织，产生中毒反应
Tonsillectomy commonly used local anesthesia, a small number of patients in the injection of local anesthetic sudden loss of consciousness, convulsions, cyanosis, respiratory arrest, blood pressure, and even death and other serious complications of cardiac arrest. We think it is a poisoning reaction. The virulence test in rabbits showed that plasma concentration of 1% lidocaine at the same dose in the pharyngeal mucosa compared with intravenous injection at different time points, the plasma concentration was determined by fluorescence polarization immunoassay (FPLA) method, statistically No significant difference (P> 0 05). Description of anesthetic in the mucosa rich in blood vessels can be quickly absorbed or may be stray into the blood vessels of anesthetic, instantaneous anesthetic into the blood circulation, more than the body to eliminate the rate of anesthetic immediately to a high blood concentration reached the heart and brain tissue, toxic reactions