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1995年在藁城市农村进行了4-7月龄婴儿接种沪191麻疹疫苗(MV)临床反应和血清学效果观察,以及对婴儿母亲麻疹抗体的监测。结果表明:婴儿的母亲麻疹抗体阳性率为8I.15%,几何平均滴度倒数(GMRT)为373。4~7月龄婴儿胎传抗体阳性率仅为2.17%,为6一7月龄婴儿接种0.2ml或0.5mlMV,免疫成功率均80%,GMRT为252-356;4月龄婴儿接种0.2ml和0.5mlMV,免疫成功率分别为33.33%和28.57%,GMRT分别为159和122:5月龄婴儿接种02ml和0.5mlMV免疫成功率分别为50.00%和71.43%,GMRT分别为200和244。婴儿自身免疫系统的发育完善似乎是决定能否免疫成功的主要因素。接种MV高热率(>38.6℃)为5.38%,皮疹率为10%。
In 1995, the clinical response and serological observation of measles vaccine (MV) in infants aged 4-7 months and the monitoring of measles antibody in infants’ mothers were carried out in Baocheng rural areas. The results showed that: the positive rate of maternal measles antibody in infants was 8I. 15%, geometric mean titer reciprocal (GMRT) was 373. 4-to 7-month-old infant fetus antibody positive rate of only 2.17%, 6 to 7 months old infants vaccinated 0.2ml or 0.5mlMV, immune success The rates of immunization were 33.33% and 28.57%, respectively. The GMRT rates were 159 and 122: 5 months old infants, respectively The vaccination success rates of vaccination with 02ml and 0.5mlMV were 50.00% and 71.43% respectively, and GMRT was 200 and 244, respectively. The development of the baby’s own immune system seems to be a major factor in determining the success of immunization. Vaccination MV fever rate (> 38.6 ℃) was 5.38%, rash rate was 10%.