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目的 通过比较芪参复康胶囊与红景天高原环境下抗焦虑抗抑郁,观察芪参复康胶囊在高原应激条件下抗焦虑抗抑郁的效果。方法 从某部高原外训部队抽取一个连队86例,随机分为芪参复康胶囊组35例,红景天组30例,安慰剂组21例。进驻高原前两周开始预防性服药,进驻高原继续服药两周(海拔4300m),采用焦虑自评量表SAS和抑郁自评量表SDS分别评定焦虑和抑郁情绪。结果 官兵在进驻高原后均引起一定的焦虑抑郁情绪。进驻高原后,芪参复康胶囊组的焦虑分数显著低于安慰剂组(t=3.61,P<0.05),与红景天组相比,焦虑分数差异无统计学意义(t=1.01,P=0.32)。芪参复康胶囊组的抑郁分数比安慰剂组与红景天组均降低(P<0.05)。结论 芪参复康胶囊具有明显的抗焦虑抗抑郁的作用,抗焦虑作用与红景天相当,抗抑郁作用优于红景天。
Objective To compare the anti-anxiety and anti-depression of Qishen Fukang capsule and Rhodiola plateau, and to observe the anti-anxiety and anti-depression effect of Qishen Fukang capsule under high altitude stress. Methods A total of 86 patients from a military training unit in a plateau were randomly divided into three groups: 35 cases in the Qishenfukang capsule group, 30 cases in the Rhodiola group and 21 cases in the placebo group. Preventive medication was started two weeks before entering the plateau and continued for two weeks in the plateau (4300 m above sea level). Anxiety and depression were assessed using the Self-rating Anxiety Scale SAS and Depression Self-rating Scale SDS. The results of officers and soldiers stationed in the plateau have caused some anxiety and depression. After entering the plateau, the anxiety scores of Qishen Fukang capsule group were significantly lower than those of placebo group (t = 3.61, P <0.05). There was no significant difference in anxiety scores between the two groups (t = 1.01, P = 0.32). The depression score of Qishen Fukang capsule group was lower than that of placebo group and Rhodiola (P <0.05). Conclusion Qishen Fukang Capsule has significant anti-anxiety and anti-depression effects, anti-anxiety and Rhodiola is equivalent, antidepressant effect is better than Rhodiola.