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目的:分析TRUST联合TPPA检测在梅毒诊断中的应用价值。方法:随机抽取我所自2013年3月至2016年3月收治的梅毒患者326例,对其进行TRUST联合TPPA检测,分析其检测结果以及两种检测方法的灵敏度以及阳性率。结果:326例患者均进行了TRUST联合TPPA检测,其中TPPA阳性296例,TRUST阳性67例,TPPA在胎传梅毒、隐性梅毒、三期梅毒、二期梅毒以及一期梅毒上的阳性率依次为100%、95.30%、100%、94.12%、96.81%、98.46%;TRUST的阳性率依次为65.20%、56.25%、100%、93.57%、73.26%、63.24%。TRUST与TPPA在胎传梅毒、隐性梅毒、一期梅毒以及灵敏度方面存在显著差异,具有统计学意义(P<0.05);TRUST与TPPA在二期梅毒以及三期梅毒方面的灵敏度以及阳性检出率差异不显著,无统计学意义(P>0.05)。结论:TRUST联合TPPA检测在梅毒诊断中具有一定的临床价值,有助于临床医师更好的为患者诊治疾病。
Objective: To analyze the value of TRUST combined with TPPA in the diagnosis of syphilis. Methods: 326 patients with syphilis who were admitted to our hospital from March 2013 to March 2016 were randomly selected. TRUST combined with TPPA test was used to analyze their test results and the sensitivity and positive rate of the two test methods. Results: The TRUS combined TPPA test was performed in 326 patients, of which 296 were TPPA-positive and 67 were TRUST-positive. The positive rates of TPPA on fetal syphilis, latent syphilis, tertiary syphilis, secondary syphilis and primary syphilis were in turn The positive rates of TRUST were 65.20%, 56.25%, 100%, 93.57%, 73.26%, 63.24% respectively. The positive rates of TRUST were 100%, 95.30%, 100%, 94.12%, 96.81% and 98.46%, respectively. There was significant difference between TRUST and TPPA in fetal syphilis, latent syphilis, primary syphilis and sensitivity (P <0.05). The sensitivity of TRUST and TPPA in secondary syphilis and tertiary syphilis were also positive The difference was not significant, no statistical significance (P> 0.05). Conclusion: TRUST combined with TPPA test has certain clinical value in the diagnosis of syphilis, which helps clinicians to better diagnose and treat the disease for patients.