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自身混合淋巴细胞反应(Autologousmixed lymphocyte reaction,AMLR)是近年来建立的测定细胞免疫反应的一种方法。由于参与反应的各个成分均采自同一个体,且是体外免疫反应,因为在AMLR过程中可产生记忆性与特异性,故测定结果基本上可反映该个体内发生的免疫反应。真实性高于目前所用的细胞免疫试验;又测定结果以反应细胞摄取~3H-TdR多少来表示,因而有较高的灵敏性。Wekaler等认为AMLR还与识别正常免疫应答中发生的自身MHC决定簇有关。最近,
Autologous mixed lymphocyte reaction (AMLR) is a method established in recent years to measure the cellular immune response. Since all the components involved in the reaction are collected from the same individual and are an in vitro immune response, since the memory and specificity can be generated during AMLR, the results of the assay essentially reflect the immune response that occurs in the individual. The authenticity is higher than the cellular immunity test used at present; And the determination result reacts with the cellular uptake ~ 3H-TdR how much to express, therefore has higher sensitivity. Wekaler et al. Conclude that AMLR is also associated with the identification of self-MHC determinants that occur in the normal immune response. recent,