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目的为了提高对罕见病例的诊断水平,本文分析了支气管肺类癌致抗利尿激素分泌不适当综合症(SIADH)的临床和病理特点。方法讨论一例患者的诊断过程及术中分别抽取进入肿瘤的动、静脉血查ADH水平,结果明显高于正常,术后病理诊断为支气管肺非典型类癌,使用多克隆ADH抗体对肿瘤组织行免疫组织化学染色阳性。结果支气管肺非典型类癌异位分泌ADH导致SIADH。结论支气管肺非典型类癌是不同于燕麦细胞癌等的另一种能导致SIADH的肺部肿瘤
Objective In order to improve the diagnosis of rare cases, this paper analyzed the clinical and pathological features of inappropriate antidiuretic hormone secretion syndrome (SIADH) caused by bronchopulmonary carcinoma. Methods To discuss the diagnosis process of one patient and the level of ADH in the blood and venous blood samples taken into the tumor during operation. The results were significantly higher than normal. The postoperative pathological diagnosis was atypical bronchopulmonary carcinoma. Polyclonal ADH antibody was used to treat tumor tissue. Positive immunohistochemical staining. Results Ectopic secretion of ADH from bronchopulmonary atypical carcinoids resulted in SIADH. Conclusion Atypical bronchopulmonary carcinoid is another lung tumor that causes SIADH, unlike Oat cell carcinoma