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鼻咽癌单纯外照射治疗有很高的局部复发率。腔内照射可作为增强局部剂量的方法,但如果病变侵犯颅底,内照射的治疗往往不充分。为提高局控率,作者在分割外照射后对原发灶进行了立体定向放射治疗的研究。 作者报道了23例接受立体定向放射治疗加量的鼻咽癌患者,1992年10月至1998年5月在斯坦福大学医学中心接受诊治均为活检证实。WHO分类,1类(鳞癌)3例,2类(非角化性癌)5例,3类(未分化癌)14例,梭形细胞癌1例。患者平均年龄43岁
Nasopharyngeal simple external beam irradiation has a high local recurrence rate. Endovascular irradiation can be used as a method to enhance the local dose, but if the lesions invade the base of the skull, treatment with internal irradiation is often inadequate. In order to improve the local control rate, the author studied the stereotactic radiotherapy of the primary tumor after the external irradiation was divided. The authors reported 23 patients with nasopharyngeal carcinoma who received stereotactic radiotherapy plus biopsy at the Stanford University Medical Center from October 1992 to May 1998. WHO classification, type 1 (squamous cell carcinoma) in 3 cases, type 2 (non-keratinizing carcinoma) in 5 cases, type 3 (undifferentiated carcinoma) in 14 cases, spindle cell carcinoma in 1 case. The average age of patients was 43 years