毛果芸香碱眼液局部用药导致全身中毒者并不多见,我院曾遇2例。病例1,患者女性,53岁。因右眼闭角型青光眼急性发作局部滴用1%毛果芸香碱眼液,因效果不明显而频繁滴眼,4小时大约滴用5.0ml,而后开始全身出汗、乏力、心慌、胸闷、气短、口流涎、站立不稳,7小时后急诊来院。体检:患者神志清楚,血压90/60mmHg,心率80次/分,律整,双肺可闻及细小水泡音,其余未见异常。眼部检查:视力右眼0.1,左眼1.0,右 Pilocarpine eye drops local medication lead to systemic poisoning are rare, our hospital had 2 cases. Case 1, female patient, 53 years old. Due to acute right angle closed-angle glaucoma local drip 1% pilocarpine eye drops, due to the effect is not obvious and frequent eye drops, drip drip 4 hours about 5.0ml, and then began sweating, fatigue, palpitation, chest tightness, shortness of breath, mouth Salivation, standing firm, emergency room to go to hospital after 7 hours. Physical examination: patients conscious, blood pressure 90 / 60mmHg, heart rate 80 beats / min, law, the lungs can be heard and small blisters sound, the rest without exception. Eye examination: right eye 0.1, left eye 1.0, right