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患者男,20岁,既往无过敏史。因皮疹3天、巩膜,皮肤黄染一天,于1983年8月22日住院。住院前因发烧,咽痛曾连服复方新诺明3天,总量达4.5g时,全身皮肤出现荨麻疹样皮疹,伴有寒战,发热(38~38.5℃)。同时有恶心,呕吐,水样腹泻及心悸等症状。体检:体温36.7℃,脉搏76次,血压110/70。全身皮肤有散在的丘疹样荨麻疹,皮肤巩膜中度黄染,心肺正常。肝脾未扪及,肝区无压痛或叩击痛。实验室检查:红细胞365万、Hb9g%,白细胞11,800,中性80%、淋巴20%,网织红细胞4.6%,血小板11.6万。红细胞脆性试验:开始溶血0.4%,完全溶血0.34%。尿常规正常。尿胆红质阴性,尿
Male patient, 20 years old, no history of allergy. Due to rash 3 days, sclera, skin yellow dye one day, in August 22, 1983 hospitalization. Before hospitalization due to fever, sore throat, even with the compound cotrimoxazole 3 days, the total amount of 4.5g, urticaria skin rash, accompanied by chills, fever (38 ~ 38.5 ℃). At the same time nausea, vomiting, watery diarrhea and heart palpitations and other symptoms. Physical examination: body temperature 36.7 ℃, pulse 76 times, blood pressure 110/70. Whole body skin scattered papules urticaria, the skin sclera moderate yellow dye, normal heart and lung. No palpable liver and spleen, liver tenderness or percussion pain. Laboratory tests: RBC 3.65 million, Hb 9g%, WBC 11,800, Neutral 80%, Lymph 20%, Reticulocyte 4.6%, Platelet 116,000. Erythrocyte fragility test: start hemolysis 0.4%, complete hemolysis 0.34%. Urine routine normal. Urine bilirubin negative, urine