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在布鲁杆菌病中,5~10%发生慢性感染性神经布鲁杆菌病(NB)。本文分析了NB 的临床表现,特别强调临床与放射学特征;介绍了本病的分型并评价了其化疗效果及结局。1984~1986年间共收治布鲁杆菌病400例,其中13例为NB。男7女6。年龄3~70岁。诊断标准为:(1)神经机能障碍不能用其他神经疾病解释;(2)CSF 蛋白和淋巴细胞增高;(3)血液和CSF 布鲁杆菌凝集试验(IgG)阳性,滴度分别超过1/640和1/128;(4)化疗有效。除调查了职业,生乳摄入史及全身性布鲁杆菌病征外,分别完成了血和CSF
Chronic Brucellosis (NB) occurs in 5 to 10% of brucellosis cases. This article analyzes the clinical manifestations of NB, with particular emphasis on clinical and radiological features; introduced the classification of the disease and evaluated its efficacy and outcome of chemotherapy. From 1984 to 1986, a total of 400 brucellosis cases were treated, of which 13 were NB. Male 7 female 6. Age 3 to 70 years old. The diagnostic criteria were: (1) neurological dysfunction could not be explained by other neurological diseases; (2) CSF protein and lymphocyte increased; (3) blood and CSF Brucella agglutination test (IgG) were positive with titers exceeding 1/640 And 1/128; (4) Chemotherapy effective. In addition to investigating occupations, history of milk intake, and systemic Brucella disease, blood and CSF