【摘 要】
：
objective;To probe into the mechanism of moxibustion preconditioning in preventive brain-protecting effect.Methods;The global brain ischemia rat model was devel
【机 构】
：
Henan College of Traditional Chinese Medicine,Zhengzhou 450008,China“,”Zhejiang Hospital of TCM, Han
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objective;To probe into the mechanism of moxibustion preconditioning in preventive brain-protecting effect.Methods;The global brain ischemia rat model was developed by blocking 4 artenes.Seventy-eight Wistarmale rats were randomly divided into 5 groups;a nomal control group,a sham-operation group,a brain ischemia group,a brain ischemia preconditioning group,a moxibustion pretreating group.The brains in the 5groups were taken at 24 h,48h,and 72h after operation respectively Superoxide dismulase(SOD)activity was determined with xanthine oxidase method and malondialdehyde(MDA)content with thiobarbituric acid method.Results;After the operation,in the moxibustion preconditioning group,SOD activity significantly increased,especially 24h after moxibustion preconditioning;and MDA content decreased,with a very significant difference as compared with that of the cerebral ischemia group(P＜0.01).Conclusion;Moxibustion preconditioning protects the ischemic and anoxic brain tissue by increasing the activity of endogenous antioxidase.
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