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周围神经损伤,根据其不同性质,Seddon将它分为三类:1.神经功能失用;2.轴突断裂;3.神经干断裂。Sunderland又将它进一步分为五度:1度,神经传导功能失用;2度,轴突断裂;3度,神经纤维断裂;4度,神经束断裂;5度,神经干断裂。上述两种分类,在神经病理学上,除第一种类型——神经功能失用外,其他类型都属于Wallerian变性。在这种变性,神经纤维的所有结构都有改变。有关对神经功能失用的认识,不少人认为是一种功能性损伤,神经纤维的结构没有变化。
Peripheral nerve injury, according to its different nature, Seddon will be divided into three categories: 1. Neurological dysfunction; 2. axon rupture; 3. nerve trunk fracture. Sunderland then further divided it into five degrees: 1 degree, nerve conduction failure; 2 degrees, axon rupture; 3 degrees, nerve fiber rupture; 4 degrees, nerve bundle break; 5 degrees, nerve trunk fracture. The above two categories, neuropathology, in addition to the first type - neurological dysfunction, the other types are Wallerian degeneration. In this denaturation, all structures of nerve fibers change. Concerns about the loss of neurological function, many people think it is a functional injury, the structure of nerve fibers has not changed.