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输血是乙型肝炎病毒(HBV)感染的主要传播途径之一。为防止HBV的感染,我市大部分献血员,均注射了乙肝疫苗。但乙肝疫苗接种人体后,引起的抗-HBs的产生存在明显的个体差异。为考察国产乙肝疫苗应答结果及我市献血员HBV感染的情况,我们对经乙肝疫苗注射后1.5～2年的470名献血员进行了HBsAg、抗-HBs、抗-HBc的检测,现报告如下: 材料与方法 1.对象:1988年2月至10月,经体格检查合格,肝功能及HBsAg均正常的470名献血员,乙肝疫苗经皮下接种三次(时间间隔0、一月、六月)每次10μg。 2.疫苗:乙肝疫苗均系卫生部北京生物制品
Blood transfusion is one of the main routes of transmission of hepatitis B virus (HBV) infection. In order to prevent the infection of HBV, most of our blood donors are injected with hepatitis B vaccine. However, there is a clear individual difference in the generation of anti-HBs after hepatitis B vaccination. In order to investigate the results of domestic hepatitis B vaccine response and HBV infection of blood donors in our city, we tested the anti-HBs and anti-HBc of 470 blood donors from 1.5 to 2 years after hepatitis B vaccine injection and are reported as follows : Materials and Methods 1. Subjects: From February to October 1988, 470 blood donors who passed the physical examination, whose liver function and HBsAg were normal, were vaccinated three times (interval 0, January, June) Each 10μg. 2. Vaccine: Hepatitis B vaccine are the Ministry of Health Beijing biological products