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目的评价国产人绝经期促性腺激素(HMG)在难治性多囊卵巢综合征促排卵体外受精胚胎移植助孕治疗中的效果。方法回顾分析国产HMG促排卵治疗难治性多囊卵巢综合征不孕患者中,35例因卵泡生成过多改行取卵体外受精胚胎移植术的临床资料。结果每周期获卵子(8±4)个,受精率60%,临床妊娠11例,妊娠率31%。费用约为采用降调节果纳芬促排卵的1/9。结论难治性多囊卵巢综合征国产HMG促排卵,如果卵泡过多,改行取卵体外受精胚胎移植助孕是有效且经济的治疗方法。
Objective To evaluate the effect of home-made human menopausal gonadotropin (HMG) in the treatment of refractory polycystic ovary syndrome (ovulation induction) by in vitro fertilization embryo transfer. Methods Retrospective analysis of domestic HMG ovulation induction treatment of refractory polycystic ovary syndrome infertility patients, 35 cases of follicular overgrowth due to the development of ovulation in vitro fertilization embryo transfer clinical data. Results Each cycle, the number of eggs was (8 ± 4), fertilization rate was 60%, clinical pregnancy rate was 11 and pregnancy rate was 31%. The cost is about 1/9 of ovulation reduction using fruit navelin. Conclusion Indwelling HMG promotes ovulation in patients with refractory polycystic ovary syndrome. If the ovarian follicles are overgrowth, it is an effective and economical treatment to transfer embryos by IVF embryo transfer.