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目的探讨腹腔镜卵巢子宫内膜异位囊肿剥除术中应用垂体后叶素水分离法的疗效。方法根据随机数字表法将行腹腔镜卵巢子宫内膜异位囊肿剥除术治疗的120例患者分为观察组与对照组,每组60例,再将观察组和对照组中的双侧囊肿患者定义为A组和B组。观察组术中使用垂体后叶素水分离法,对照组术中未使用垂体后叶素水分离法,对比各组患者之间的疗效。结果 1观察组与对照组患者手术成功率相比差异无统计学意义(P>0.05)。2观察组手术时间、术中出血量显著低于对照组(P<0.05),两组患者术后体温、术后肛门排气时间相比差异无统计学意义(P>0.05)。3手术前,A组与B组的雌二醇(E2)、卵泡刺激素(FSH)、促黄体生成素(LH)相比差异无统计学意义(P>0.05)。术后6个月,A组患者E2显著高于B组(P<0.05),FSH、LH显著低于B组(P<0.05)。4观察组有5例患者使用垂体后叶素后出现一过性血压升高、心率加快,未给予特殊处理即恢复正常,不良反应发生率为8.3%。结论腹腔镜卵巢子宫内膜异位囊肿剥除术中应用垂体后叶素水分离法的效果确切,既可以降低手术操作难度,还有利于保护患者卵巢功能,且不良反应可控。
Objective To investigate the curative effect of pituitrin-water separation in laparoscopic ovarian endometriosis cyst excision. Methods According to the random number table method, 120 patients who underwent laparoscopic ovarian endometriosis were divided into observation group and control group, with 60 cases in each group. The bilateral cysts in observation group and control group Patients were defined as Group A and Group B. Observation group intraoperative use of pituitrin water separation method, the control group did not use pituitrin water separation method to compare the efficacy of each group of patients. Results 1 There was no significant difference in the surgical success rate between the observation group and the control group (P> 0.05). The operation time and intraoperative blood loss in the observation group were significantly lower than those in the control group (P <0.05). There was no significant difference in postoperative body temperature and postoperative anal exhaust time between the two groups (P> 0.05). There was no significant difference in estradiol (E2), follicle stimulating hormone (FSH) and luteinizing hormone (LH) between group A and group B before operation (P> 0.05). At 6 months after operation, E2 in group A was significantly higher than that in group B (P <0.05), FSH and LH were significantly lower than those in group B (P <0.05). 4 In the observation group, 5 patients had transient hypotension after pituitrin, the heart rate was accelerated, and returned to normal without any special treatment. The incidence of adverse reactions was 8.3%. Conclusion Laparoscopic ovarian endometriosis cyst stripping pituitrin water separation method is effective, can reduce the difficulty of surgical operations, but also help to protect patients with ovarian function, and adverse reactions can be controlled.