人们早已认识到良性肝病是引起甲状腺机能异常的一种原因。循环血甲状腺素(T_4)99.9%以上与产生于肝脏的结合蛋白[最重要的是T_4结合球蛋白(TBG)]结合,各种肝病(包括肝硬化和肝炎)都可引起该结合蛋白水平发生改变。从而出现循环T_4水平异常,这已有很多报道。本文报道1例甲状腺机能正常的肝细胞癌并TBG增多的患者,甲状腺素水平增高呈进行性上升与恶性肿瘤进 It has long been recognized that benign liver disease is a cause of thyroid dysfunction. More than 99.9% of circulating thyroxine (T_4) binds to the liver-derived binding protein [most importantly, T_4 binding globulin (TBG)] and can cause this binding protein level to occur in a variety of liver diseases, including cirrhosis and hepatitis change. There is a lot of reports about abnormal T_4 circulating level. This article reports a case of normal thyroid function of hepatocellular carcinoma and TBG increased in patients with elevated thyroid hormone was progressive and malignant tumor