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1990年以来我科应用盐酸纳洛酮治疗急性酒精中毒获得满意疗效,报告如下: 急性酒精中毒一般分三期:兴奋期、共济失调期、昏睡及昏迷期,我们共收治40例病人,其中兴奋期4例(10％),共济失调期10例(25％),昏睡昏迷期26例(65％)。男性32例,女性8例,年龄18～43岁,平均25岁,饮酒量200～400毫升,以就诊次序随机分为治疗组和对照组,每组20例,两组性别年龄,病情基本相似(P>0.05)。治疗组兴奋期给予50％葡萄糖40毫升加入纳洛酮0.4～0.8毫升静脉注射或纳洛酮0.4～0.8毫克静推,平均20分钟清醒,共济失调组药量0.8～1.2毫克,平均30分钟
Since 1990, our department of naloxone hydrochloride treatment of acute alcoholism obtained satisfactory results, the report is as follows: Acute alcoholism generally divided into three phases: excitement, ataxia, lethargy and coma, we received a total of 40 patients, of which Excitement in 4 cases (10%), ataxia in 10 cases (25%), coma and unconsciousness in 26 cases (65%). There were 32 males and 8 females, aged from 18 to 43 years, with an average of 25 years old and drinking amount of 200 to 400 ml. They were randomly divided into treatment group and control group with 20 cases in each group. The two groups were similar in gender and age, (P> 0.05). The treatment group excitement given 50% glucose 40 ml add naloxone 0.4 ~ 0.8 ml intravenous injection or naloxone 0.4 ~ 0.8 mg static push, an average of 20 minutes awake, ataxia group 0.8 to 1.2 mg, an average of 30 minutes