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本文对黄石市橡胶行业1971年1月1日至1973年12月31日在岗1223名工人进行恶性肿瘤回顾性队列研究表明,橡胶恶性肿瘤占死因首位,其全部肿瘤,男、女肿瘤死亡分别为112.03/10万、158.26/10万、62.49/10万,与对照组比较,标准化相对危险度(SRR)分别为2.50、2.62、2.27;与当地人群比较SMR分别为257、208、220,均有统计学意义。RSMR分析提示男性肝癌、胃癌、鼻咽癌,女性白血病、乳腺癌等多个部位肿瘤死亡增加。本研究还提示该行业恶性肿瘤高发可能与亚硝胺类、防老剂D、苯等有害因素的联合作用有关。
Retrospective cohort study of 1,223 workers in Huangshi rubber industry from Jan. 1, 1971 to Dec. 31, 1973 showed that the number of deaths from rubber malignancies was the highest, and the deaths of all tumors, male and female tumors were 112.03 / 100000, 158.26 / 100000, 62.49 / 100000. Compared with the control group, the standardized relative risk (SRR) were 2.50, 22.62, and 2.27, respectively. Compared with the local population, the SMRs were 257,208,220, Statistical significance. RSMR analysis showed that there was an increase in the death of cancer in many parts of liver cancer, gastric cancer, nasopharyngeal cancer, leukemia, breast cancer and other parts of men. This study also suggests that the high incidence of malignant tumors in the industry may be related to the combined effects of nitrosamines, antioxidant D, benzene and other harmful factors.