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目的 :考察复方丹参注射液与右旋糖酐 4 0葡萄糖注射液的配伍稳定性。方法 :将配伍液室温放置 6h ,观察其外观、pH值、不溶性微粒以及复方丹参注射液中的活性成分原儿茶醛和右旋糖酐 4 0葡萄糖注射液中的右旋糖酐 4 0的含量变化。结果 :配伍液pH值、外观、含量均无明显变化。但 2 ,5 μm以上微粒数在考察时间内随着配伍液放置时间的增加而增多 ,10 μm以上 ,2 5 μm以上微粒数基本不变。 结论 :复方丹参注射液与右旋糖酐 4 0葡萄糖注射液配伍室温放置 6h内稳定。
OBJECTIVE: To investigate the compatibility of Fufang Danshen injection with dextran 40 glucose injection. Methods: The compatibility of the solution was placed at room temperature for 6h. The changes of dextran 40 content in protocatechuic aldehyde and dextran 40 glucose injection were observed by the appearance, pH value, insoluble particles and compound Danshen injection. Results: There was no obvious change in the pH value, appearance and content of compatibility solution. However, the number of particles above 2 μm and 5 μm increased with the increase of the time of compatibility solution. The number of particles above 10 μm and 25 μm remained unchanged. Conclusion: The compound Danshen injection and dextran 40 glucose injection compatibility at room temperature within 6h stability.