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ＩｇＡ肾病（ＩｇＡＮ）与人类白细胞抗原（ＨＬＡ）关联但机制不明，肿瘤坏死因子（ＴＮＦ）基因位于ＨＬＡ区域，并被发现在ＩｇＡＮ的发病中起作用。我们用聚合酶链反应／限制性酶切片段长度多态性（ＰＣＲ／ＲＦＬＰ）方法对ＩｇＡＮ患者进行ＴＮＦＢ等位基因检测，旨...
IgA nephropathy (IgAN) is associated with human leukocyte antigen (HLA) but its mechanism is unknown. The tumor necrosis factor (TNF) gene is located in the HLA region and was found to play a role in the pathogenesis of IgAN. We used the polymerase chain reaction / restriction fragment length polymorphism (PCR / RFLP) method of IgAN patients TNFB allele detection, purpose ...