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目的：验证橘善宝（血栓烷合成酶抑制剂）对改善急性期脑血栓患者的运动功能障碍及生活能力的临床疗效。方法：对６０例颈内动脉系统脑血栓患者的神经功能缺损程度及生活能力进行治疗前后的自身对照评价。结果：在自觉症状和神经功能缺损两项中，治疗前后比较有明显改善（Ｐ＜０．０１）；在生活能力评价中，生活自理不能由原来的５３．４％下降为１７％。不良反应发生率为６．７％。结论：橘善宝对改善急性期脑血栓所致的运动功能障碍及提高患者的生活能力有较好的疗效，毒副作用少，有比较广泛的应用范围。
OBJECTIVE: To verify the clinical efficacy of TZS (thromboxane synthase inhibitor) in improving motor dysfunction and life skills in patients with acute cerebral thrombosis. Methods: The self-control evaluation of the degree of neurological deficits and the viability of 60 patients with ICA cerebral thrombosis before and after treatment. Results: There were significant differences in both symptoms and neurological deficits before and after treatment (P <0.01). In the assessment of life skills, the self-care of living can not be reduced from 53.4% to 17%. The incidence of adverse reactions was 6.7%. CONCLUSION: Tianshanbao has better curative effect on improving motor dysfunction caused by cerebral thrombosis in acute stage and improving the living ability of patients, with less toxic and side effects and wider range of application.