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通过整群抽样,对中国北方獐子岛地区进行调查与体检,分析高尿酸血症与MS各组分的相关性及患病情况。结果高尿酸血症患者肥胖发生率为63.83%(OR=2.31,95%CI:1.46~3.68);高血压的发生率为31.52%(OR=3.07,95%CI:1.84~5.09);高甘油三脂血症发生率为31.52%(OR=2.74,95%CI:1.72~4.36)。对MS的患病风险的OR值分析显示了随年龄的增长而上升的增龄性。以CDS标准分析,40~59岁组MS的患病风险是<40岁组的13.27倍,而≥60岁组的患病风险是<40岁组的21.07倍。结论高尿酸血症与MS各组分关系密切,獐子岛地区属沿海岛屿,常年食用大量富含嘌呤的海产品,本研究结果提示该地区高尿酸血症及MS含征的患病率均较高。
Through cluster sampling, the investigation and physical examination of Zhangzidao area in northern China were conducted to analyze the correlation and prevalence of hyperuricemia and various MS components. Results The incidence of obesity in patients with hyperuricemia was 63.83% (OR = 2.31, 95% CI: 1.46-3.68). The incidence of hypertension was 31.52% (OR = 3.07, 95% CI: 1.84-5.09) The incidence of triglyceride was 31.52% (OR = 2.74, 95% CI: 1.72-4.46). The odds ratio (OR) analysis of the prevalence of MS showed an increasing age-related increase with age. According to the CDS criteria, the prevalence of MS in the 40- to 59-year-old group was 13.27 times higher than that in the 40-year-old group, and 21.07-fold in the group of ≥60 years. Conclusions Hyperuricemia is closely related to each component of MS. Zhangzidao is a coastal island with large quantities of purine-rich marine products. The results suggest that the prevalence of hyperuricemia and MS in the area is higher than that of MS high.