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该书自出版以来,畅销全国各地,受到了临床医师们的欢迎。全书共分三篇十章,全书在注意应用有关抗生素的现代科学理论的基础上,着重分析了滥用抗生素的危害性,阐述了合理应用抗生素的重要意义,以及在不同条件下合理应用抗生素的原则与措施。是目前一本很有实用价值的有关抗生素的合理应用方面的重要参考书。读后,也发现了该书仍存有某些不足之处,现提出如下几点看法,供参考。一、102页青霉素G的抗菌作用:“属于肠杆菌科的革兰氏阴性杆菌,如大肠杆菌,副大肠杆菌、产气杆菌、……等,对青霉素G都不敏感。”但据文献记载,此药对革兰氏阴性的奇异变形杆菌,体外试验优于四环素,对产碱杆菌胜于链霉素,有人曾以此药治疗某些产气杆菌败血症与伤寒带菌者均获得了良好的效果;并认为,当患者有肝、肾疾病时,应该使用青霉素G。此外,大剂量的青霉素G对大肠菌杆,绿脓杆菌等亦有效。
The book since its publication, sold throughout the country, has been welcomed by clinicians. The book is divided into three ten chapters, the book is paying attention to the application of modern scientific theory of antibiotics, focusing on the analysis of the dangers of abuse of antibiotics, described the importance of rational use of antibiotics, and the principle of rational use of antibiotics under different conditions And measures. Is a very practical value of the rational application of antibiotics an important reference book. After reading, but also found that there are still some deficiencies in the book, the following points are made for reference. The antibacterial effect of penicillin G: “Gram-negative bacilli belonging to Enterobacteriaceae such as Escherichia coli, Escherichia coli, Aerobacter aerogenes, ... are insensitive to penicillin G.” However, according to the literature , The drug on Gram-negative Proteus mirabilis, in vitro test is superior to tetracycline, Alcaligenes bacteria than streptomycin, some people have been using this drug to treat some of Aerobacter septicemia and typhoid carriers have obtained a good Effect; and that, when patients with liver and kidney disease, penicillin G should be used. In addition, large doses of penicillin G on coliform bacteria, Pseudomonas aeruginosa, also effective.