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目的:研究肥胖与儿童睡眠呼吸障碍的相关性。方法:选取年龄大于7岁的肥胖儿童为研究对象,对其进行血常规、动脉血气分析等检查,并进行问卷调查及多导睡眠监测,并选取同期就诊的体重正常的儿童为对照组。结果:在不伴扁桃体、腺样体肥大(ATH)的肥胖儿童中,阻塞性睡眠呼吸暂停/低通气综合征(OSAHS)31例,占50.80%,而对照组儿童不存在OSAHS,不伴ATH的两组儿童OSAHS发生率存在统计学差异(P<0.05)。在伴ATH的肥胖儿童中,OSAHS为117例,占81.25%,而对照组儿童OSAHS例数为84例,占61.76%,伴ATH的两组儿童OSAHS发生率比较无统计学差异(P>0.05)。肥胖,腺样体大、扁桃体大为OSAHS发病的高危因素。BMI Z值与最低血氧饱和度呈负相关(r=-0.31,P<0.05),而与Lg AHI呈正相关(r=0.38,P<0.05)。结论:肥胖是导致儿童出现睡眠呼吸障碍的高危因素,睡眠障碍的严重程度与肥胖程度密切相关。
Objective: To study the correlation between obesity and sleep apnea syndrome in children. Methods: Obese children older than 7 years old were selected as study subjects. Blood routine examination, arterial blood gas analysis and other tests were performed. Questionnaires and polysomnography were also performed. Children of normal weight were selected as the control group. Results: Among obese children without tonsil, adenoid hypertrophy (ATH), OSAHS was found in 31 cases (50.80%), while OSAHS was absent in control children There was a significant difference in OSAHS incidence between the two groups (P <0.05). Among obese children with ATH, OSAHS was found in 117 cases (81.25%), while OSAHS in control group was 84 cases (61.76%). There was no significant difference in the incidence of OSAHS among children with ATH (P> 0.05 ). Obese, adenoid, tonsil are the risk factors of OSAHS. The BMI Z value was negatively correlated with the lowest oxygen saturation (r = -0.31, P <0.05), but positively correlated with Lg AHI (r = 0.38, P <0.05). Conclusion: Obesity is a risk factor for children with sleep-disordered breathing. The severity of sleep-disturbances is closely related to the degree of obesity.