C-带异染色质的变异是一种有趣的人类多态性。其发生机制和分子构成尚未完全明了。近数十年里,许多研究已经指出,肿瘤患者的结构上C-带变异的发生率一般要比对照组高。这种关系在1号染色体上表现得尤为明显。因而认为异染色质多态性是促使伴有遗传和细胞遗传改变的肿瘤易于发生的一种因素。可是,很少有人报道个体范围内异 C-heterochromatin variation is an interesting human polymorphism. Its mechanism and molecular composition are not yet completely understood. In recent decades, many studies have pointed out that the incidence of structural C-band variation in cancer patients is generally higher than in the control group. This relationship is particularly evident on chromosome 1. So that heterochromatin polymorphism is to promote genetic and cytogenetic changes associated with the tumor prone to a factor. However, few people report differences within the individual