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克隆病的临床活动度、内镜下表现和生物学参数之间的关系尚未彻底研究。本研究旨在前瞻性探讨静止期或活动期结肠及回结肠克隆病患者上述三者的关联。 方法:对121例患者相继用下述力法检测:用克隆病活动度指数(CDAI)测量临床活动度;用标准方式记录分析内镜下克隆病活动指数(CDEIS);另检测血清白蛋白、α_2-球蛋白、α_1-抗胰蛋白酶、血清粘蛋白、C反应蛋白、红细胞沉降率、血小板、淋巴细胞及多形核细胞计数,红细胞压积和粪便α_1-抗胰蛋白酶含量作为生物学参数。
The clinical activity of Crohn’s disease, the relationship between endoscopic findings and biological parameters have not been thoroughly investigated. This study was designed to prospectively investigate the association of these three in patients with colon and colon-versus-colon disease in quiescent or active stage. Methods: One hundred and twelve patients were tested with the following methods: the activity of Clonal Disease Activity Index (CDAI) was measured; the activity of Clone Disease Index (CDEIS) was recorded and recorded by standard method; the serum albumin, alpha 2 -globin, alpha 1-antitrypsin, serum mucin, C-reactive protein, erythrocyte sedimentation rate, platelet count, lymphocyte and polymorphonuclear cell count, hematocrit and fecal α 1 -antitrypsin content were used as biological parameters.