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分析８例肾淀粉样变性的临床、病理及免疫病理特点，并在国内首次川肾组织免疫球蛋白ｋ，λ轻链、血清淀粉Ａ蛋白（ＳＡＡ）染色及高锰酸钾试验辅助分型。结果显示；①淀粉样变性多见于５０岁以上患者，常表现为多系统损害伴有典型肾病综合征；②肾脏病理改变以“肾小球系膜区结节状硬化和非增殖、非炎症性变化”为特征。免疫病理常呈多种免疫球蛋白、补体共同沉积的“满堂红”现象；③７例ＡＬ型与１例ＡＡ型淀粉样变的肾脏病理改变类似，但前者有ｋ、λ轻链的沉积，后者可检出ＳＡＡ。高锰酸钾试验阴性３例均为ＡＬ型，阳性１例为ＡＡ型。
The clinical, pathological and immunopathological characteristics of 8 patients with renal amyloidosis were analyzed. The first accessory immunofluorescence kappa lambda light chain, serum amyloid A protein (SAA) staining and potassium permanganate test were used in this study. The results showed that: ① amyloidosis more common in patients over the age of 50, often manifested as multiple system damage associated with typical nephrotic syndrome; ② pathological changes of the kidney glomerular mesangial nodular sclerosis and non-proliferation, non-inflammatory Change “is characterized. Immunopathology often showed a variety of immunoglobulins, complement co-deposition of ”full house red" phenomenon; ③ 7 cases of AL and 1 case of AA amyloidosis pathological changes in the kidney similar, but the former k, λ light chain deposition, the latter SAA can be detected. Negative potassium permanganate test in 3 cases were AL type, positive in 1 case of AA type.