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1.重组人血清白蛋白rHSA(1g/Kg)显著减少由嘌呤霉毒氨基核苷引起的肾病的小鼠腹水量。2.在本动物模型中利尿磺胺(1-30mg/Kg)不能明显减少腹水。3.rHSA(1g/Kg)联合利尿磺胺(5mg/Kg)与仅用利尿磺胺相比,在本动物模型中能显著减轻此种腹水。4.鉴于此,rHSA可用作从人血浆提取的人血清白蛋
1. Recombinant human serum albumin rHSA (1 g / Kg) significantly reduces ascites volume in mice with nephropathy induced by puromycin aminonucleosides. 2. Levofloxacin (1-30 mg / Kg) did not significantly reduce ascites in this animal model. 3. RHSA (1g / Kg) combined with diurethamine (5mg / Kg) compared with only the use of diuretic sulfonamide in this animal model can significantly reduce such ascites. 4. In view of this, rHSA can be used as human serum albumin extracted from human plasma