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目的 复方血栓通胶囊的功效为活血化淤、益气养阴，既往多用于眼科疾患，但临床也有扩大运用于心血管系统疾病的报道。为了证实其药理作用，我们观察了该药对实验性犬缺血心肌的保护作用。方法 采用结扎冠状动脉左前降支的方法复制急性心肌缺血模型。全程检测血压，实验结束时取左室缺血区心肌检测超氧物歧化酶（SOD）、丙二醛（MDA）、糖原、乳酸、乳酸脱氢酶(LDH) 等生化指标。结果 复方血栓通高、低剂量组血压和SOD活性均显著高于缺血组，与对照组和地奥组比较无显著差异，其MDA、LDH含量均显著低于缺血组，与对照组和地奥组比较无显著差异。结论 复方血栓通胶囊对实验性犬缺血心肌具有保护作用。
Objective The efficacy of compound Xueshuantong Capsule is to promote blood circulation and reduce stasis, improve nourishing yin and nourishing yin. It has been used in ophthalmology for a long time. However, clinical application has also been reported in cardiovascular diseases. In order to confirm its pharmacological effects, we observed the protective effects of this medicine on experimental canine ischemic myocardium. Methods The model of acute myocardial ischemia was reproduced by ligating left anterior descending coronary artery. Blood pressure was measured throughout the experiment. At the end of the experiment, myocardial biochemical indexes such as superoxide dismutase (SOD), malondialdehyde (MDA), glycogen, lactic acid and lactate dehydrogenase (LDH) were measured. Results The blood pressure and SOD activity in compound thrombosis high and low dose groups were significantly higher than those in ischemic group. There were no significant differences between the two groups in the content of MDA and LDH, Di Austrian group was no significant difference. Conclusion Compound Xueshuantong capsule has protective effect on experimental canine ischemic myocardium.