人表皮生长因子(Epidermal growth factor,EGF)也称尿抑胃素(Urogastrone),主要在十二指肠Brunner氏腺产生。EGF具有多种生物学作用,可刺激或抑制细胞的增殖,促进细胞的分化。EGF最近还被认为是一种脑肠肽,有神经传导和神经递质的功能。EGF在体外可以刺激多种间质及内皮细胞的生长,是无血清培养基的重要成分。日本和澳大利亚的科学家 Epidermal growth factor (EGF), also known as Urogastrone, is produced primarily in the duodenum Brunner’s gland. EGF has a variety of biological effects, can stimulate or inhibit the proliferation of cells, and promote cell differentiation. EGF has recently also been considered as a ghrelin, a neurotransmitter and neurotransmitter function. EGF can stimulate a variety of stromal and endothelial cell growth in vitro, is an important component of serum-free medium. Japanese and Australian scientists