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目的研究普拉洛芬联合杞菊地黄丸治疗干眼症的临床效果。方法选取通化市五三一医院从2014年9月-2015年9月就诊的142例干眼症患者,按照就诊顺序进行排号,单号71例划入观察组,予以普拉洛芬联合杞菊地黄丸治疗,双号71例划入对照组,予以玻璃酸钠滴眼液治疗,治疗9周后,对比两组的治疗效果。结果观察组症状缓解率、基础泪液分泌、角膜荧光素染色降低率、泪膜破裂时间均大于对照组,差异具有统计学意义(P<0.05)。结论普拉洛芬联合杞菊地黄丸治疗干眼症较玻璃酸钠滴眼液有效。普拉洛芬联合杞菊地黄丸有效缓解干眼症患者症状,增加泪液分泌,延长泪膜破裂时间,减轻角膜上皮损伤。
Objective To study the clinical effect of pranoprofen combined with Qiju Dihuang Pills in the treatment of dry eye syndrome. Methods A total of 142 patients with dry eye from September 2014 to September 2015 in Tongxiang Hospital were enrolled in this study. According to the order of treatment, 71 patients were assigned to the observation group and treated with pranoprofen combined with Qiju Dihuang Wan treatment, double number 71 cases were assigned to the control group, to be sodium hyaluronate eye drops treatment, after 9 weeks of treatment, the two groups compared the therapeutic effect. Results The symptom relief rate, basal lacrimal fluid secretion, corneal fluorescein staining rate and tear film rupture time were all higher in the observation group than those in the control group, with statistical significance (P <0.05). Conclusions Pranoprofen combined with Qijudihuang Pill is effective in treating dry eye compared with sodium hyaluronate eye drops. Pranoprofen combined Qijudihuang Pills effectively relieve the symptoms of patients with dry eye, increase tear secretion, prolong the tear film rupture time, reduce corneal epithelial injury.