谷氨酸是人及哺乳动物中枢神经系统中含量最多的兴奋性神经递质 ,在神经元存活、突触可塑性维持 ,脑发育调节以及学习记忆等多种功能中发挥重要作用 ,然而过量谷氨酸所引起的兴奋毒性与多种疾病 ,诸如 :缺血或缺氧性脑损伤、癫、帕金森病、肌萎缩侧索硬化等 ,本文将阐述谷氨酸及其受体与多发性硬化之间的关系。 Glutamic acid is the most abundant excitatory neurotransmitter in the central nervous system of humans and mammals and plays an important role in many functions such as survival of neurons, maintenance of synaptic plasticity, regulation of brain development and learning and memory. However, excessive glutamine Excitotoxicity caused by acid and a variety of diseases, such as: ischemic or hypoxic brain injury, epilepsy, Parkinson’s disease, amyotrophic lateral sclerosis, etc., this article will explain the glutamate and its receptor and multiple sclerosis The relationship between.