论文部分内容阅读
目的 :研究乳腺癌中晚期患者行乳腺癌根治术后放化疗的影响。方法 :选择2014年6月至2015年6月我院接收治疗的乳腺癌中晚期患者50例为研究对象,所选患者均行乳腺癌根治术~+放疗~+化疗治疗,对患者治疗前后相关免疫指标与治疗后患者生存率进行分析。结果 :治疗后,患者CD_4~+、CD_8~+、CD_4~+、CD_4~+/CD_8~+、NK的值均较治疗前低,差异具备统计学意义(P<0.05)。经1年的随访,患者局控率为82%,生存率为92%。结论 :在对乳腺癌中晚期患者实施乳腺癌根治术后,给予放疗与化疗会对患者机体免疫力造成一定影响,因此,在治疗时应该充分考虑这方面的不良反应,以患者实际情况为依据选择治疗方案,以实现理想的临床效果。
Objective: To study the effect of radiotherapy and chemotherapy after radical mastectomy for advanced breast cancer patients. Methods: From June 2014 to June 2015, 50 cases of advanced breast cancer patients who received treatment in our hospital were selected as the study subjects. The patients who underwent radical mastectomy ~ + radiotherapy ~ + chemotherapy were selected. The patients were treated before and after treatment Immune index and survival after treatment were analyzed. Results: After treatment, the values of CD_4 ~ +, CD_8 ~ +, CD_4 ~ +, CD_4 ~ + / CD_8 ~ + and NK in patients were lower than those before treatment, with statistical significance (P <0.05). After a year of follow-up, the patient control rate was 82%, the survival rate was 92%. CONCLUSIONS: Radiotherapy and chemotherapy given to patients with advanced breast cancer after radical mastectomy have some impact on the patient’s immune system. Therefore, adverse reactions should be fully considered in the treatment, based on the actual situation of the patients Choose treatment options to achieve the desired clinical outcome.