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目的:通过分析某中青年体检人群的体成分的分布情况,探索体内胰岛素水平的影响因素,为胰岛素水平的估计提供简便快捷的方法。方法:(1)选取某医院健康体检人群共205人,测空腹状态下的体成分、血糖(FBG)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDLC)、胰岛素等。胰岛素取自然对数,记为Lnins。(2)比较不同年龄组,不同性别上述指标的差异,以及中心性肥胖率的差异。并以Lnins为因变量,建立多元线性回归方程。结果:(1)各年龄组身高、体重、腰围、身体质量指数(BMI)、LDL-C及TG男性均高于女性,差异有统计学意义(P<0.05);随着年龄增加,平均体重、腰围、体脂肪率、BMI、FBG逐渐升高,女性平均Lnins有下降趋势。(2)在20~岁和30~岁年龄组,男性中心性肥胖发生率高于女性,差异有统计学意义,P<0.05;随着年龄的上升,男性和女性中心性肥胖发生率逐渐升高,女性增速更快。(3)Lnins的影响因素为BMI、年龄,回归方程Y=0.036+0.084×BMI-0.007×年龄,R2=0.262,P<0.01。结论:同年龄组比,男性发生肥胖,血糖升高、血脂紊乱等代谢性疾病的风险更高;随着年龄增长,各项指标均朝向不利于健康的方向发展,且女性更为显著。Lnins与BMI呈正相关,与年龄呈负相关。
OBJECTIVE: To explore the distribution of body composition of a young and middle-aged medical population and to explore the influencing factors of insulin level in vivo so as to provide a quick and easy method for the estimation of insulin level. Methods: (1) A total of 205 healthy people in a hospital were selected to measure body composition, blood glucose (FBG), triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C ), Low density lipoprotein cholesterol (LDLC), insulin and the like. Insulin natural logarithm, denoted as Lnins. (2) to compare the different age groups, gender differences in the above indicators, as well as the central obesity rate differences. Lnins as the dependent variable, the establishment of multiple linear regression equation. Results: (1) The height, weight, waist circumference, body mass index (BMI), LDL-C and TG in all age groups were significantly higher than those in women (P <0.05) , Waist circumference, body fat percentage, BMI, FBG gradually increased, the average female Lnins have a downward trend. (2) The prevalence of central obesity in males was higher than that in females in the age of 20 ~ 30 and the age of 30 ~ (P <0.05). The incidence of central obesity in men and women increased gradually with age High, women grow faster. (3) The influencing factors of Lnins were BMI, age, regression equation Y = 0.036 + 0.084 × BMI-0.007 × age, R2 = 0.262, P <0.01. CONCLUSION: Compared with the same age group, men are at higher risk of metabolic diseases such as obesity, hyperglycemia and dyslipidemia. With age, all indicators are unfavorable to health development, and women are more significant. Lnins was positively correlated with BMI and negatively correlated with age.