在过去的两年,Roussel—UCLAF对R U486进行了大量的研究,检查了在非常早期的妊娠和月经周期之末给予RU486单次剂量600mg的作用。作者在408例确诊为妊娠的妇女应用了单次剂量的RU486,350倒闭经<41天,58倒闭经>42天。闭经<41天者成功率为84%,闭经>42天者仅为58%,妊娠未完全中止和未排净前者为5%,后者为21%,继续妊娠前者为11%,后者为21%。给予RU486单次剂量600mg后,无子宫出血的妇女是非常少的,通常<2%,大多数妇女出血在≤3天开始,最迟不超过第8天。然而,大约20%的病人出血时间≥14天,有时出血非常严重,一般多于正常周期。 In the past two years, Roussel-UCLAF has conducted extensive research into R U486 to examine the effect of a single RU486 dose of 600 mg administered at the very early gestation and menstrual cycles. The authors applied a single dose of RU486 to 408 women diagnosed with pregnancy, and the failure occurred after <41 days and 58 days after failure> 42 days. The success rate of amenorrhea <41 days was 84%, amenorrhea> 42 days was only 58%, pregnancy was not completely suspended and the net is not discharged the former was 5%, the latter was 21%, the former is 11% of the latter, the latter is twenty one%. Given RU486 single dose of 600mg, there are very few women who have no uterine bleeding, usually <2%, and most women start bleeding ≤3 days and not later than day8. However, about 20% of patients have a bleeding time of ≥14 days, sometimes bleeding is very serious, usually more than the normal cycle.