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调查东海县农民糖尿病(DM)、糖耐量减低(IGT)的患病率及影响因素。2598名25岁以上农民空腹进食100g面粉馒头。测定餐后2h指尖血糖,同时测量血压、身高、体重并计算体重指数(BMI),凡餐后血糖≥7.1mmol/L(130mg/dl)者做口服75g葡萄糖耐试验(OGTT)。DM、IGT诊断按1985年WHO标准执行。查出DM52人,患病率2.00%,标化为2.44%;查出IGT81人,患病率3.10%,标化为3.90%。显示DM、IGT患病率随年龄增加而增加(P<0.001),而与性别无差异(P<0.05);BMI≥25的DM、IGT患病率明显高于BMI<25者(P<0.001);高血压合并DM、ICT,显著高于血压正常者(P<0.001)。DM、IGT空腹胰岛素显著高于正常组(P<0.01),而胰岛素敏感指数低于正常组(P<0.01)。农民中DM、IGT的患者比1979年以来国内调查结果明显升高。农民生活水平的提高、田间体力劳动减少、年龄、肥胖、高血压、胰岛素抵抗等是农民DM、IGT患病增加的影响因素。
To investigate the prevalence and influencing factors of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in Donghai County. 2598 farmers over the age of 25 fasting eat 100g flour bread. The blood glucose, body mass and body mass index (BMI) were measured at 2h after meal, and 75g oral glucose tolerance test (OGTT) was given after every postprandial glucose≥7.1mmol / L (130mg / dl). DM, IGT diagnosis according to the 1985 WHO standards. Detected DM52 people, the prevalence of 2.00%, standardized 2.44%; detected IGT81 people, the prevalence of 3.10%, standardized 3.90%. The prevalence of DM and IGT increased with age (P <0.001), but not with gender (P <0.05). The prevalence of DM and IGT with BMI≥25 was significantly higher than that with BMI <25 ); Hypertension with DM, ICT, was significantly higher than those with normal blood pressure (P <0.001). Fasting insulin in DM and IGT was significantly higher than that in normal group (P <0.01), while insulin sensitivity index was lower than normal group (P <0.01). Farmers in the DM, IGT patients since 1979, the domestic survey results were significantly higher. Increasing living standards of peasants, reducing manual labor in the field, and age, obesity, hypertension and insulin resistance are the influential factors for increasing DM and IGT in peasants.