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成纤维细胞生长因子 (fibroblastgrowthfactor,FGF)是一个包括多个成员的多肽家族 ,在细胞的分化和发展中起到一系列重要作用。它们具有许多生物学特性 ,尤其是在促有丝分裂和血管形成方面。FGF的活性主要是通过结合和激活其受体FGFR来实现的。FGFs/FGFRs信号传递与肿瘤的发生?
Fibroblast growth factor (FGF) is a multi-member family of polypeptides that play a series of important roles in the differentiation and development of cells. They have many biological properties, especially in mitosis and angiogenesis. FGF activity is mainly through the binding and activation of its receptor FGFR to achieve. FGFs / FGFRs signaling and tumorigenesis?