考虑到毛细管色谱分析过程中径向浓度梯度对传质过程的影响，建立了相应的色谱质量平衡模型，模仿Ｇｉｄｄｉｎｇｓ的假设，将模型适当化简，并通过数学变换的方法得到了流出曲线的一级矩及二、三级中心矩表达式。结果表明，溶质的径向扩散不仅对柱效、峰展宽、峰形特征等有影响，而且对溶质的保留时间也有一定的影响。 Taking into account the influence of radial concentration gradient on mass transfer process during capillary chromatography analysis, a corresponding chromatographic mass balance model was established to simulate the assumption of Giddings. The model was simplified and the effluent curve was obtained by mathematical transformation Moment and two, three center moment expression. The results show that the radial diffusion of solute not only affects the column efficiency, peak broadening and peak shape, but also affects the retention time of solute.