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目的:探讨孕妇年龄、产次与妊娠期并发症及妊娠结局的相关性。方法:回顾性分析2016年1月至2018年8月在枣庄市妇幼保健院分娩且信息齐全的5 283例产妇的临床资料及妊娠结局。根据产妇分娩时的年龄分为低龄组(2次生产，256例)。对三组不同年龄及不同产次产妇的临床资料进行对照分析，分析孕产妇年龄、产次与妊娠结局之间的关系。结果:低龄组、高龄1组和高龄2组产妇孕期吸烟史、孕前超重肥胖、妊娠合并子宫肌瘤、既往子宫肌瘤剔除术史比较差异有统计学意义(n P<0.05)。初产组、经产1组和经产2组产妇孕期吸烟史、孕前超重肥胖、妊娠合并子宫肌瘤、既往子宫肌瘤剔除术史比较差异有统计学意义(n P<0.001)。低龄组、高龄1组和高龄2组胎儿染色体异常发生率[0.36%(6/1 761)、1.20%(34/2 821)、3.00%(21/701)]和新生儿窒息发生率[0.53%(9/1 761)、1.31%(37/2 821)、3.43%(24/701)]比较差异有统计学意义(n P<0.05)。初产组、经产1组和经产2组胎儿染色体异常发生率[0.89%(32/3 596)、1.47%(21/1 431)、3.21%(8/256)]和新生儿窒息发生率[0.78%(28/3 596)、2.31%(33/1 431)、3.60%(9/256)]比较差异有统计学意义(n P<0.05)。低龄组、高龄1组和高龄2组产妇妊娠期高血压疾病、妊娠期糖尿病、胎膜早破、早产发生率比较差异有统计学意义(n P<0.05)。分娩次数、产妇年龄与妊娠期并发症存在显著的相关关系(n P<0.05)。n 结论:随着孕产妇年龄及产次的增加，妊娠期并发症及妊娠不良结局的风险随之增加，应加强高龄孕产妇妊娠的管理，对妊娠期并发症及合并症尽早进行预防及干预。“,”Objective:To investigate the correlation of maternal age and delivery times with pregnancy complications and pregnancy outcome.Methods:The clinical data and pregnancy outcomes of 5 283 women who delivered in Zaozhuang Maternal and Child Health Hospital from January 2016 to August 2018 with complete data were retrospectively analyzed. According to the age of delivery, they were divided into the younger group ( 2 times, 256 cases). The clinical data were compared and analyzed among three groups with different delivery ages, and among three groups with different delivery times. And the relationship of maternal age and delivery times with pregnancy outcome was analyzed.Results:There were significant differences in smoking history during pregnancy, overweight and obesity before pregnancy, pregnancy complicated with uterine fibroids, and previous myomectomy history among the younger group, the older group 1, and the older group 2 (n P<0.05). There were significant differences in smoking history during pregnancy, overweight and obesity before pregnancy, pregnancy complicated with uterine fibroids, and previous myomectomy history among primigravida group, multigravida group 1, and multigravida group 2 (n P<0.001). The incidence of fetal chromosomal abnormalities of the younger group, older group 1, and older group 2 were 0.36%(6/1 761), 1.20%(34/2 821) and 3.00%(21/701), respectively, and the incidence of neonatal asphyxia in the three groups were 0.53% (9/1 761), 1.31% (37/2 821) and 3.43%(24/701), respectively; the incidences of fetal chromosomal abnormalities and neonatal asphyxia were significant different among the three groups (n P<0.05). The incidence of fetal chromosomal abnormalities in primigravida group, multigravida group 1, and multigravida group 2 were 0.89% (32/3 596), 1.47% (21/1 431) and 3.21% (8/256), respectively, and the incidences of neonatal asphyxia were 0.78% (28/3 596), 2.31% (33/1 431), 3.60%(9/256), respectively; the incidences of fetal chromosomal abnormalities and neonatal asphyxia were significant different among the three groups (n P<0.05). The incidences of pregnancy induced hypertension, gestational diabetes mellitus, premature rupture of membranes, and preterm birth were significantly different among the younger group, older group 1, and older group 2 (n P<0.05). The delivery times and maternal age were correlated with pregnancy complications (n P<0.05).n Conclusions:With the increase of maternal age and delivery times, the risk of pregnancy complications and adverse pregnancy outcomes increase. It is necessary to strengthen the management of elderly pregnant women and to prevent and intervene the complications of pregnancy as soon as possible.