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目的探讨慢性炎性脱髓鞘性神经病（ＣＩＤＰ）的电生理特点。方法对１６例ＣＩＤＰ患者的运动神经１０８条、感觉神经６２条及６８块肌肉进行ＥＭＧ、运动神经传导速度（ＭＣＶ）、远端潜伏期、Ｆ波的出现率、潜伏期及波形，感觉神经传导速度（ＳＣＶ）测定。采用分段刺激记录各段刺激引出的复合肌肉动作电位（ＣＭＡＰ）的波幅、时限和面积，而后进行近端与远端比，从而判断传导阻滞（ＣＢ）及一过性离散（ＴＤ）。结果每例均有３条以上神经受累，上、下肢神经远端潜伏期延长为６２．１％，ＭＣＶ减慢为７０．７％，Ｆ波异常为６９．５％，Ｈ反射异常为３８．９％，ＣＢ、ＴＤ和ＣＢ／ＴＤ异常共５７．０％，其中ＣＢ为２９．３％，腋、肌皮、桡、面神经异常为７３．０％，ＳＣＶ减慢为７２．６％。ＥＭＧ神经源性改变为７３．５％。结论ＣＩＤＰ为广泛的周围神经远、近端损害，近端显著，感觉、运动均受累，存在以脱髓鞘为主伴有轴索变性的电生理改变。电生理的无创性、简便及可重复性使其成为ＣＩＤＰ极为重要的诊断手段。
Objective To investigate the electrophysiological characteristics of chronic inflammatory demyelinating neuropathy (CIDP). Methods EMG, motor nerve conduction velocity (MCV), distal latency, incidence of F wave, latency and wave shape, sensory nerve conduction velocity (MVD) in 108 cases of motor nerve and 62 muscles of sensory nerve in 16 patients with CIDP were measured. SCV) assay. The amplitude, time and area of compound muscle action potential (CMAP) induced by each segment of stimulation were recorded by segmental stimulation, and then the proximal and distal ratio was compared to determine the conduction block (CB) and transient dispersion (TD). Results There were more than 3 nerve involvement in each case. The distal latency of upper and lower extremity nerves was prolonged by 62.1%, MCV slowed down to 70.7%, abnormal F wave was 69.5% and abnormal H reflex was 38.9 The abnormalities of%, CB, TD and CB / TD were 57.0%, CB was 29.3%. The axillary, muscular skin, radial and facial nerve abnormalities were 73.0% and SCV was 72.6%. Neurogenic changes in EMG were 73.5%. Conclusion CIDP is extensive and peripheral nerve damage, proximal injury, proximal significant, sensory and motor involvement, there is demyelination associated with axonal degeneration electrophysiological changes. Electrophysiological noninvasive, simple and reproducible make it an extremely important diagnostic tool for CIDP.